Compounded Ketamine
Compare quotes for compounded Ketamine, see whether a prescription is needed, what affects price, how fast quotes come back, and what happens after you submit.
Check Ketamine Prices by Form, Strength and Quantity
Pharmacies in our network list compounded Ketamine from $55 to $300 per fill across 13 listed prices. Pick what your prescription calls for to see the range pharmacies list for it, then send those details straight into the quote form.
Ranges come from the price lists pharmacies in our network share with us for quoting, limited to pharmacies that can take your request, and they are not a quote. Shipping, dispensing fees and the exact prescription change the price; your quotes carry the real numbers and the pharmacy behind each one.
About Ketamine
Compounded ketamine is prescribed under physician supervision for treatment-resistant depression, PTSD, chronic pain, and certain anxiety disorders. Compounding pharmacies prepare ketamine in formulations not commercially available — sublingual troches, intranasal sprays, rapid-dissolve tablets, and oral solutions — making at-home dosing possible under provider oversight. Ketamine is a DEA Schedule III controlled substance; compounded ketamine requires a prescription from a DEA-registered provider. Compounded ketamine is distinct from Spravato (esketamine), which is FDA-approved for in-clinic administration only.
Clinical uses of compounded ketamine
The largest clinical use today is treatment-resistant depression (TRD) and PTSD, delivered under ketamine-assisted therapy (KAT) protocols by licensed providers. At-home sublingual troches and intranasal sprays supervised by a prescriber have become common — they deliver psychedelic-threshold doses without requiring repeated clinic visits.
Other clinical uses include: chronic neuropathic pain (oral solutions, transdermal combination creams with ketorolac, lidocaine, or gabapentin), complex regional pain syndrome, cancer-related breakthrough pain, and off-label treatment of severe anxiety in selected patients. These off-label uses are clinically established but not FDA-approved.
Common formulations
The most-prescribed compounded ketamine formulations are: sublingual troches (50–200 mg per troche, dosed 1–2 times per week for mental-health protocols); intranasal sprays (10–50 mg per spray); rapid-dissolve tablets (similar dosing to troches); and oral solutions (for titrated pain protocols).
For chronic pain, topical creams combining ketamine with other analgesics (ketorolac, bupivacaine, gabapentin, amitriptyline) are common. These are usually custom-formulated for the individual patient based on pain-type and tolerance.
Compounded ketamine vs Spravato
Spravato (esketamine) is an FDA-approved nasal spray containing only the S-enantiomer of ketamine, administered in a certified clinic under REMS supervision. It's covered by many commercial insurance plans for TRD but requires in-clinic observation for two hours after each dose.
Compounded ketamine contains racemic ketamine (both R- and S-enantiomers) and can be dispensed as troches, nasal sprays, or oral solutions for at-home use under provider supervision. The compounded version is paid out of pocket (typically $150–$400/month including clinic fees) but allows at-home administration. Clinical evidence supports both options; the choice depends on patient preference, access, and cost.
Typical compounded ketamine pricing
Sublingual troches typically run $150–$350 for a 30-day supply depending on strength and quantity. Intranasal sprays run $200–$450 per 30-day supply. Oral solutions for chronic pain are typically $100–$250 per 30-day supply.
Topical combination pain creams vary widely based on ingredient mix — typically $75–$200 per 60-gram tube. Prices for the same prescription can differ widely between pharmacies, so it is worth comparing quotes before your first fill.
Key Questions Before You Request Quotes
Can I get Ketamine compounded?
Possibly. A licensed prescriber has to decide whether Ketamine is appropriate, and a licensed compounding pharmacy has to confirm it can legally prepare the requested strength, form, and quantity.
Is a prescription needed?
Yes. Patient-specific 503A compounding is based on a valid prescription order or prescriber notation for an identified patient.
What affects price?
Strength, dosage form, quantity, ingredient sourcing, sterile versus non-sterile preparation, shipping requirements, and each pharmacy's workflow can all change the final quote.
How fast can I get quotes?
For routable requests, Compounding Finder typically returns quote options by email within 1-2 business days after you submit the request details.
What happens after I submit?
We review the request, route it to eligible licensed pharmacies, collect available options, and email you the quoted choices. You decide whether to move forward with a pharmacy.
Source notes: FDA explains that compounded drugs are not FDA-approved finished products and describes 503A compounding around patient-specific prescriptions. See Compounding and the FDA and Section 503A.
Related Ketamine Quote Pages
How to Get Ketamine Quotes
Ketamine by State
Compare Ketamine prices from licensed compounding pharmacies in your state:
Why Compare Ketamine Prices?
Prices for the same compounded prescription often differ widely between pharmacies — on almost half of the requests we compared (all medications combined), the highest quote was at least double the lowest. Factors that affect pricing include the pharmacy’s location, their ingredient sourcing, and compounding volume.
By comparing quotes from multiple licensed pharmacies, you can find the best combination of price, quality, and convenience without spending hours making phone calls.
Frequently Asked Questions
Can I get ketamine for depression through a compounding pharmacy?
Yes, when prescribed by a licensed provider in the context of a real clinical relationship. Most at-home ketamine therapy is delivered as compounded sublingual troches or intranasal sprays prescribed by ketamine-assisted-therapy clinics or telehealth-based providers. Federal DEA rules on telehealth prescribing of controlled substances have been extended multiple times — verify current status with your provider.
How is compounded ketamine different from Spravato?
Spravato (esketamine) is an FDA-approved nasal spray containing only the S-enantiomer, administered in a certified clinic under REMS supervision. Compounded ketamine contains racemic ketamine (both enantiomers) and can be prepared as troches, nasal sprays, or oral solutions for at-home use under prescriber supervision. Spravato is insurance-covered; compounded ketamine is typically paid out of pocket but allows at-home dosing.
Is compounded ketamine safe for at-home use?
When prepared by a licensed compounding pharmacy and used under provider supervision at appropriate doses, compounded ketamine has a reasonable safety profile for most adults. Risks include dissociation, blood pressure changes, bladder irritation with prolonged high-dose use, and potential for abuse or dependency. Patients with a history of psychosis, uncontrolled hypertension, or substance use disorder should discuss risks carefully with their provider before starting.
How much does compounded ketamine cost?
Sublingual troches typically run $150–$350 for a 30-day supply. Intranasal sprays are $200–$450 per 30-day supply. Oral solutions for chronic pain run $100–$250 per 30-day supply. Topical combination pain creams vary widely — typically $75–$200 per 60-gram tube. Total cost usually includes clinic oversight fees that vary by provider.
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