Compounded Low-dose naltrexone (LDN)
Compare quotes for compounded Low-dose naltrexone (LDN), see whether a prescription is needed, what affects price, how fast quotes come back, and what happens after you submit.
About Low-dose naltrexone (LDN)
Low-dose naltrexone (LDN) refers to naltrexone prescribed at much lower strengths than standard commercially manufactured naltrexone tablets. In the United States, LDN is commonly compounded when a prescriber needs patient-specific strengths such as 0.5 mg to 4.5 mg, an oral liquid for titration, or an excipient profile that is not available from a manufactured product.
Compounded LDN in the USA
Compounded LDN in the USA is low-dose naltrexone prepared by a licensed compounding pharmacy when a prescriber needs a low strength or dosage form that is not commercially available. Standard naltrexone tablets are commonly manufactured at 50 mg, while LDN prescriptions are often written for much lower strengths such as 0.5 mg, 1.5 mg, 3 mg, or 4.5 mg.
A valid prescription is required. Compounding Finder does not prescribe LDN or decide whether LDN is appropriate for a patient; that decision belongs to the patient's licensed clinician and dispensing pharmacist.
Common LDN forms and strengths
The most common compounded LDN form is an oral capsule. Pharmacies may also prepare oral liquid for patients who need slower titration, sublingual tablets or troches for patients who prefer a dissolving form, and topical preparations when specifically prescribed.
Prescriptions should state the exact strength, dosage form, quantity, directions, and any inactive ingredient requirements. This matters for patients who need dye-free, gluten-free, lactose-free, or other excipient-specific formulations.
How LDN pricing is compared
LDN pricing varies by strength, dosage form, quantity, pharmacy workflow, shipping, and whether the prescription requires special inactive ingredients. A 30-day capsule prescription is usually priced differently from a titration liquid or a 90-day supply.
The pricing range on this page is based on active pharmacy price listings tracked by Compounding Finder. It is not a guaranteed quote. Submit your prescription details to compare current prices from licensed pharmacies that can evaluate the actual formulation.
Safety and legality notes
FDA says compounded drugs are not FDA-approved, which means FDA does not verify the safety, effectiveness, or quality of each compounded preparation before it is marketed. Patients should use licensed U.S. pharmacies, avoid sellers that ship without a prescription, and ask the pharmacy about quality standards for the dosage form being dispensed.
LDN is often discussed for immune, pain, and inflammatory conditions, but off-label use should be evaluated by a clinician who knows the patient's history, medications, and opioid exposure risk.
Key Questions Before You Request Quotes
Can I get Low-dose naltrexone (LDN) compounded?
Possibly. A licensed prescriber has to decide whether Low-dose naltrexone (LDN) is appropriate, and a licensed compounding pharmacy has to confirm it can legally prepare the requested strength, form, and quantity.
Is a prescription needed?
Yes. Patient-specific 503A compounding is based on a valid prescription order or prescriber notation for an identified patient.
What affects price?
Strength, dosage form, quantity, ingredient sourcing, sterile versus non-sterile preparation, shipping requirements, and each pharmacy's workflow can all change the final quote.
How fast can I get quotes?
For routable requests, Compounding Finder typically returns quote options by email within 1-2 business days after you submit the request details.
What happens after I submit?
We review the request, route it to eligible licensed pharmacies, collect available options, and email you the quoted choices. You decide whether to move forward with a pharmacy.
Source notes: FDA explains that compounded drugs are not FDA-approved finished products and describes 503A compounding around patient-specific prescriptions. See Compounding and the FDA and Section 503A.
Typical Low-dose naltrexone (LDN) Pricing
Prices vary by dosage, formulation, quantity, and pharmacy. The range above reflects listings currently tracked by Compounding Finder and is not a guaranteed quote. Submit a request below to get a personalized quote for your specific needs.
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How to Get Low-dose naltrexone (LDN) Quotes
Low-dose naltrexone (LDN) by State
Compare Low-dose naltrexone (LDN) prices from licensed compounding pharmacies in your state:
Why Compare Low-dose naltrexone (LDN) Prices?
Compounded medication prices vary significantly between pharmacies — sometimes by 300% or more for the exact same drug, strength, and formulation. Factors that affect pricing include the pharmacy’s location, their ingredient sourcing, and compounding volume.
By comparing quotes from multiple licensed pharmacies, you can find the best combination of price, quality, and convenience without spending hours making phone calls.
Frequently Asked Questions
What is compounded LDN?
Compounded LDN is low-dose naltrexone prepared by a licensed compounding pharmacy in a patient-specific strength or dosage form. It is used when the prescriber needs a low strength, titration liquid, sublingual form, topical preparation, or excipient profile that is not available as a standard manufactured product.
Do I need a prescription for compounded LDN in the USA?
Yes. Compounded low-dose naltrexone requires a valid prescription from a licensed U.S. healthcare provider. A legitimate compounding pharmacy should not dispense LDN without a prescription.
What forms can U.S. compounding pharmacies make for LDN?
Common compounded LDN forms include capsules, oral liquid, sublingual tablets or troches, and topical preparations. Availability depends on the pharmacy, the prescription, and whether the requested formulation is appropriate for that patient.
How much does compounded LDN cost?
The cost depends on strength, form, quantity, shipping, and the pharmacy. Capsules are often the simplest option, while oral liquids, sublingual forms, topical preparations, or special excipient requests may cost more. The pricing table on this page shows active listings tracked by Compounding Finder, but a personalized pharmacy quote is needed for the exact prescription.
Is compounded LDN FDA-approved?
No. FDA says compounded drugs are not FDA-approved. Compounded LDN is prepared by a licensed pharmacy for a specific patient under a prescription; the final compounded preparation is not reviewed by FDA for safety, effectiveness, or quality before dispensing.
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