Compounded Natural Desiccated Thyroid (NDT)
About Natural Desiccated Thyroid (NDT)
Important update: as of 2026 compounded Natural Desiccated Thyroid (NDT / porcine thyroid / Thyroid USP bulk powder) is no longer available from US compounding pharmacies. The FDA issued enforcement action against unapproved animal-derived thyroid products, and licensed 503A/503B pharmacies are no longer filling compounded NDT prescriptions. FDA-approved desiccated thyroid products — Armour Thyroid, NP Thyroid, and WP Thyroid — remain available by prescription at regular retail pharmacies and contain the same T4/T3 combination. Patients who needed compounded NDT because of an allergen or filler issue may want to ask their prescriber about custom synthetic T3/T4 compounding, which is not affected by this FDA action.
We Do Not Currently Route Natural Desiccated Thyroid (NDT) Quote Requests
Compounded Natural Desiccated Thyroid (NDT / porcine thyroid / Thyroid USP) is subject to FDA enforcement action against unapproved animal-derived thyroid products. US compounding pharmacies are no longer filling NDT prescriptions. FDA-approved NDT alternatives (Armour, NP Thyroid, WP Thyroid) remain available through retail pharmacies with a prescription. If FDA guidance changes, we will revisit.
What patients use instead of compounded NDT
Desiccated thyroid is still available — just not as a compounded preparation. The FDA-approved products below contain the same porcine-derived T4/T3 combination as compounded NDT and are filled at regular retail pharmacies with a prescription from your doctor.
- Armour ThyroidFDA-approved
The original FDA-approved porcine desiccated thyroid, manufactured by AbbVie. Contains a ~4:1 T4:T3 ratio. Widely stocked at retail pharmacies.
Typically $15–$40/month with insurance; cash prices vary by pharmacy — use GoodRx to compare.
Compare Armour Thyroid prices on GoodRx → - NP ThyroidFDA-approved
FDA-approved porcine desiccated thyroid manufactured by Acella. Same active ingredient as Armour; often a lower-cost alternative.
Often the lowest-cost FDA-approved NDT option. Also stocked at Mark Cuban's Cost Plus Drugs at transparent pricing.
Compare NP Thyroid prices on GoodRx → - WP Thyroid / Nature-ThroidLimited availability
RLC Labs porcine desiccated thyroid with fewer fillers than Armour or NP. Supply has been intermittent over the last several years — check with your pharmacy before relying on it.
Check WP Thyroid availability on GoodRx → - Custom synthetic T3/T4 compoundingStill routable
If you needed compounded NDT because of an allergen or filler issue with commercial products, custom synthetic T3/T4 compounding is not affected by the FDA's NDT action. A prescriber can specify the exact T3:T4 ratio, release profile, and excipient profile you need.
Get compounded synthetic T3/T4 quotes →
Links to external price-comparison tools and retail pharmacies are provided for convenience. Compounding Finder is not affiliated with these services and does not receive information about your purchases. Always consult your prescriber before changing medications.