Cheapest Estradiol Cream: Compounding Pharmacy Prices
Real price-book figures for compounded Estradiol creams from 13 pharmacies that can quote your prescription. Compare the range, then request a personalized quote for your exact strength and quantity.
Prices as of September 2026, from pharmacy price lists shared with us for quoting. Not a quote; your prescription's strength, quantity and shipping set the final price.
Estradiol creams Price Comparison (13 pharmacies, 30 options)
Prices as of September 2026. Actual costs may vary by prescription. Pharmacies share their price lists with us for quoting, so we publish the prices without naming the pharmacy — submit a free quote request and we tell you exactly who quoted what.
| Pharmacy | Dosage | Form / Qty | Price | Lead Time |
|---|---|---|---|---|
| Cheapest option Exact pharmacy and price unlocked after request | Dose Unlocked after request | Form / Qty Formulation and quantity unlocked | Price | Lead |
| Fastest option Turnaround, pharmacy, and terms unlocked after request | Dose Unlocked after request | Form / Qty Formulation and quantity unlocked | Price | Lead |
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| Pharmacy A | 0.03% | Cream | $48.00 | — |
| Pharmacy B | 0.1-0.075mg | Patch · 8 | $50.00 | — |
| Pharmacy A | 0.25mg/0.5gm | Cream | $52.00 | — |
| Pharmacy C | Various | Cream | $54.00 | — |
| Pharmacy D | 0.2%:0.1% | Cream · 30 | $60.00 | — |
| Pharmacy E | 0.5 mg/mL | Cream · 30 | $65.00 | — |
| Pharmacy F | 0.025mg | Patch · 8 | $65.00 | — |
| Pharmacy B | 0.05mg | Patch · 4 | $70.00 | — |
| Pharmacy C | 0.5%/0.1% | Cream | $75.00 | — |
| Pharmacy G | — | Cream · 20 | $81.00 | — |
| Pharmacy E | 1/1 mg/mL | Cream · 30 | $85.00 | — |
| Pharmacy G | — | Cream · 30 | $86.00 | — |
| Pharmacy A | 0.025 mg/24 hour | — | $89.00 | — |
| Pharmacy E | 0.025 mg | Patch · 1 | $89.00 | — |
| Pharmacy A | 0.1 mg/24 hour | — | $93.00 | — |
| Pharmacy E | 0.5 mg/mL | Cream · 60 | $99.00 | — |
| Pharmacy H | 2mg/0.1mg/200mg/gm | Topical Cream · 90 | $112.50 | 3 days |
| Pharmacy I | 2mg/0.1mg/200mg/gm | Topical Cream · 90 | $120.00 | 3 days |
| Pharmacy F | 1mg/0.1 mL | Other: Topical- In pure MCT oil or Pure Olive oil without ANY additives · 261 mL | $125.00 | 1 day |
| Pharmacy F | 2mg/0.1mg/200mg/gm | Topical Cream · 90 | $125.00 | 3 days |
| Pharmacy D | 0.2%:0.1% | Cream · 90 | $150.00 | — |
| Pharmacy G | — | Cream · 90 | $182.00 | — |
| Pharmacy J | 1mg/0.1 mL | Other: Topical- In pure MCT oil or Pure Olive oil without ANY additives · 261 mL | $195.00 | 1 day |
| Pharmacy K | — | Topical Cream · 90 gm | $292.50 | 1 day |
Showing top 25 of 30 options. Get a personalized quote for your specific needs.
What a compounded Estradiol gram is
Cream here means topical and transdermal creams, gels, ointments, lotions, foams and solutions. A compounding pharmacy makes Estradiol creams to the strength on the prescription rather than stocking a fixed commercial product, which is why the same drug can be quoted at very different prices.
Strengths listed right now: 0.5 mg/mL, 1 mg/mL, 2 mg/mL, 2.5 mg/mL, 1/1 mg/mL and 1/2 mg/mL.
Common fill sizes: 8, 30, 15 and 45.
Estradiol creams: cost questions
How much do compounded Estradiol creams cost?
Across 13 compounding pharmacies in our price book, compounded Estradiol creams run typically $1.65 to $12.50 per gram, with a typical fill priced $30 to $293 per fill. The median is about $2.83 per gram. Prices are as of September 2026 and are not a quote.
What does a month of Estradiol creams cost?
It depends on the strength and how many creams a month the prescription calls for. At $1.65 to $12.50 per gram, thirty creams work out to roughly $49.50 to $375, before shipping. Larger quantities usually bring the per-gram price down.
Which strengths of Estradiol creams do pharmacies make?
Strengths currently listed include 0.5 mg/mL, 1 mg/mL, 2 mg/mL, 2.5 mg/mL and 1/1 mg/mL. Compounding pharmacies prepare the strength on the prescription, so other strengths are usually possible — ask for a quote for the exact strength your prescriber wrote.
Why are Estradiol creams priced so differently between pharmacies?
The price of a compounded gram reflects the active ingredient, the base and flavoring, the labor to make each batch, quality testing, and each pharmacy's overhead. Quantity matters too: a 90-count fill is usually cheaper per gram than a 30-count fill. Shipping and a dispensing fee can be added on top.
Do I need a prescription for compounded Estradiol creams?
Yes. Compounded Estradiol is made to a patient-specific prescription. A licensed prescriber writes the strength, form and quantity, and a licensed compounding pharmacy prepares it.
How do I get an actual quote?
Submit a free quote request with your prescription details. We send it to compounding pharmacies that make Estradiol creams and ship to your state, and email you their prices, usually within one to two business days. You pick the pharmacy; there is no charge to you.
Other ways Estradiol is compounded
Get Your Estradiol Cream Quote
Tell us the strength and quantity on your prescription and we will send it to pharmacies that make Estradiol creams and ship to you.