How to Get Low-Dose Naltrexone (LDN) Online in 2026: Prescription, Pharmacy and Real Prices

You can get low-dose naltrexone (LDN) online in the United States, legally and without leaving home. There are only three steps, and the one most people get wrong is the last one.

1. Get a prescription. Naltrexone is prescription-only. Any licensed prescriber can write it, including a telehealth provider. It is not a controlled substance, so there are no special rules about online prescribing or shipping.
2. Have a compounding pharmacy make it. Commercial naltrexone comes as 50 mg tablets. LDN doses are 0.5 mg to 6 mg, so the low-dose capsules, tablets or liquid have to be compounded to your prescription.
3. Choose the pharmacy yourself. A prescription belongs to you, not to whoever wrote it. You can send it to any licensed compounding pharmacy that ships to your state, and prices for the same capsule differ by more than three to one.

The rest of this guide covers the two ways to do this online, what each actually costs, and what to check before you order.

Why LDN has to come from a compounding pharmacy

The FDA-approved naltrexone product is a 50 mg tablet for alcohol and opioid dependence. LDN is the same drug at a fraction of that strength, prescribed off-label for conditions such as fibromyalgia, chronic pain, Crohn's disease, multiple sclerosis, Hashimoto's, long COVID and mast cell activation syndrome.

No manufacturer makes a 1.5 mg or 4.5 mg naltrexone product, so a compounding pharmacy prepares it from the pure powder in the exact strength your prescriber writes. That is why every LDN listing you see online, bundled or not, is ultimately filled by a compounding pharmacy. The question is just how many steps sit between you and that pharmacy, and what each step costs.

Typical forms:

• Capsules, by far the most common, in strengths such as 1.5 mg, 3 mg and 4.5 mg, usually in 30, 60 or 90-count fills.
• Tablets, offered by fewer pharmacies but priced similarly.
• Oral liquid, useful for titrating up from a very low dose in small steps.
• Sublingual troches and topical creams, rarer, for patients who cannot tolerate oral fillers.

If you have mast cell activation syndrome or a filler sensitivity, the filler matters as much as the strength. Ask for the exact excipient (microcrystalline cellulose, sucrose, rice flour and so on) before you commit, and say so on any quote request.

Route A: you already have a prescriber

If your own doctor or a specialist will write LDN, you are already past the expensive step. All that is left is choosing where to fill it.

Here is what LDN capsules cost at the compounding pharmacies in our price book as of September 2026:

The spread is the point. A 90-count fill of 4.5 mg capsules is priced anywhere from about $60 to well over $150 depending on the pharmacy, for the same drug at the same strength. Per month, the cheaper end works out to roughly $20 to $40, before shipping.

You can see the current per-capsule range and request quotes on our cheapest LDN capsules page, or compare all LDN pricing. A quote request is free, goes to compounding pharmacies that make LDN and ship to your state, and comes back with their prices, usually within one to two business days. You pick the pharmacy, and your prescriber sends the prescription there.

Route B: you need a prescription

If you do not have a prescriber willing to write LDN, an online telehealth visit is the usual answer. There are two kinds of service, and it pays to know which one you are looking at.

Prescription-only services evaluate you and write the prescription, then let you fill it wherever you like. Examples include the prescriber directory maintained by the LDN Research Trust, a charity that lists telemedicine prescribers who work with LDN, and consultation services such as LDN Direct and LDN Doctor. Some independent telehealth practices and functional-medicine clinics also prescribe LDN by video visit. With these, you pay for the visit and then shop the pharmacy step exactly as in Route A.

Bundles combine the prescriber visit, the compounded medication and shipping into a subscription. Advertised starting prices we saw in September 2026, as listed by the companies themselves:

Prices and terms change often, so treat the table as a snapshot, not a quote. Bundles are convenient, and at the cheapest end they are genuinely hard to beat. Before you subscribe, ask three questions:

• What does the refill cost? The headline price is often an introductory or first-month figure.
• Can I move the prescription? Legally, yes, always. In practice some bundles make the prescription live inside their own system, so ask how you get a copy.
• Which pharmacy fills it, and is it licensed in my state? A reputable service will tell you. You can check any US pharmacy license through your state board of pharmacy.

Bundle or à la carte: a worked example

Suppose your prescription is 4.5 mg capsules, one a day.

• À la carte: a one-time telehealth visit (commonly in the $50 to $150 range, sometimes covered by insurance if it is your own doctor) plus a 90-count fill from a compounding pharmacy at $60 to $120 works out to about $20 to $40 a month for the medication, once the visit is paid for.
• Bundle: $25 to $79 a month, everything included, but the price is per month for as long as you stay subscribed.

Over a year, a $25 bundle costs about the same as the à la carte route. A $75 bundle costs roughly double. The bundle wins on convenience; the à la carte route wins on price the longer you take LDN, which for most conditions is measured in years.

Can you buy LDN online without a prescription?

No. Naltrexone is prescription-only in the United States. Websites offering "no prescription needed" LDN are shipping from outside US regulation, with no assurance of the strength, purity or even the identity of what is in the capsule. Since any licensed prescriber can write naltrexone and a telehealth visit costs less than a month of most bundles, there is no reason to take that risk.

Naltrexone is also not a DEA-controlled substance. That matters for you in a good way: a compounding pharmacy in one state can ship it to you in another without the restrictions that apply to controlled medications, which is why the price comparison above spans the whole country.

What to check before you order

• Licensure. Look up the pharmacy on your state's board of pharmacy website. Non-resident pharmacies must be licensed in your state to ship to you.
• The filler. Ask what the capsule contains besides naltrexone. Sucrose, microcrystalline cellulose and rice flour are common; MCAS patients often need a specific one.
• Strength and count on the label. Confirm the pharmacy is making the strength written, not rounding to what it usually stocks.
• Beyond-use date. Compounded capsules typically carry a 90 to 180 day beyond-use date. A six-month fill can expire before you finish it.
• Turnaround and shipping. Most compounding pharmacies ship LDN within two to five business days. Shipping is often $8 to $15 unless the pharmacy includes it.
• Auto-ship terms. With a bundle, know how to pause or cancel before you enter a card.

Frequently asked questions

Can I get a naltrexone prescription online? Yes. A licensed telehealth provider can evaluate you and prescribe naltrexone, including low-dose naltrexone, because it is not a controlled substance. Some services write the prescription only; others bundle it with the medication.

How do I get an LDN prescription? Ask your own doctor first, since LDN is inexpensive and widely prescribed off-label. If they are unfamiliar with it or unwilling, the LDN Research Trust keeps a list of prescribers who work with LDN, and telehealth services such as LDN Direct, LDN Doctor, AgelessRx and Hone Health prescribe it after an online consultation.

Can I order naltrexone online? Only with a prescription. Once you have one, you can order from any licensed compounding pharmacy that ships to your state, either directly or through a quote request that lets you compare several pharmacies' prices first.

How much does LDN cost without insurance? At compounding pharmacies, LDN capsules typically run $0.67 to $2.10 each, so a 30-day supply is usually $20 to $60 and a 90-count fill $60 to $120, before shipping. Bundled telehealth subscriptions advertise $25 to $79 a month including the prescriber visit.

Does insurance cover LDN? Usually not. Compounded medications are rarely covered, and LDN is prescribed off-label. Most patients pay cash, and HSA or FSA funds can typically be used.

Do I have to use the telehealth company's pharmacy? No. A prescription is yours to fill anywhere. Ask the service for a copy of the prescription or to send it to the pharmacy you choose.

How long does it take to get LDN online? A telehealth visit is often same-day or next-day. Compounding and shipping usually add two to five business days. Quote requests through Compounding Finder typically return pharmacy prices within one to two business days.

Get LDN prices from compounding pharmacies

If you have a prescription, or a prescriber ready to write one, request free quotes for your exact strength, count and filler. We send it to compounding pharmacies that make LDN and ship to your state, and you choose the one you want.

• Cheapest LDN capsules: per-capsule prices
• Compare all compounded LDN pricing
• How much does compounded LDN cost? Full price guide
• What is LDN used for?

This guide is for information only and is not medical advice. Whether LDN is appropriate for you is a decision for a licensed prescriber. Third-party prices are as advertised by those companies in September 2026 and are not verified by Compounding Finder.