Compounded HCG (Human Chorionic Gonadotropin)
Check whether compounded HCG (Human Chorionic Gonadotropin) can be routed, what restrictions may apply, and what to ask your prescriber or pharmacist.
About HCG (Human Chorionic Gonadotropin)
Compounded HCG is no longer available: the FDA reclassified HCG as a biologic in March 2020, and biologics cannot legally be produced by US compounding pharmacies. HCG remains available as the FDA-approved commercial product — Pregnyl and generic chorionic gonadotropin (10,000 IU vials) — through regular pharmacies. Ask your prescriber to send the prescription there.
Why compounded HCG is no longer available
Until 2020, HCG was regulated as a conventional drug and compounding pharmacies could prepare it. In March 2020, HCG transitioned to regulation as a biologic under the Biologics Price Competition and Innovation Act — and biologics cannot be produced by compounding pharmacies under Sections 503A/503B. There is no shortage exception and no medical-necessity pathway. This applies industry-wide; pharmacies still marketing compounded HCG today are operating outside current FDA rules.
How to get HCG today
HCG remains fully available as an FDA-approved commercial product: Pregnyl and generic chorionic gonadotropin for injection, typically supplied as a 10,000 IU vial that is reconstituted and drawn by dose. Your prescriber sends the prescription to a regular pharmacy — most can order it, and fertility or specialty pharmacies routinely stock it. Common protocols (for example, 500–1,000 IU two to three times weekly alongside TRT, or fertility trigger dosing) all use this same vial.
What commercial HCG costs
With discount-card pricing, generic chorionic gonadotropin 10,000 IU vials typically run in the low hundreds of dollars, and one vial covers about five weeks at 1,000 IU twice weekly. Recombinant choriogonadotropin (Ovidrel) is also available for fertility trigger use. If you were quoted compounded HCG at a lower price, be aware that legitimate US pharmacies cannot legally prepare it.
Key Questions Before You Request Quotes
Can I get HCG (Human Chorionic Gonadotropin) compounded?
Not through Compounding Finder right now. A prescriber and pharmacist still have to decide whether any compounded HCG (Human Chorionic Gonadotropin) preparation is legally and clinically appropriate.
Is a prescription needed?
Yes. Patient-specific 503A compounding is based on a valid prescription order or prescriber notation for an identified patient.
What affects price?
Strength, dosage form, quantity, ingredient sourcing, sterile versus non-sterile preparation, shipping requirements, and each pharmacy's workflow can all change the final quote.
How fast can I get quotes?
For routable requests, Compounding Finder typically returns quote options by email within 1-2 business days after you submit the request details.
What happens after I submit?
We review the request, route it to eligible licensed pharmacies, collect available options, and email you the quoted choices. You decide whether to move forward with a pharmacy.
Source notes: FDA explains that compounded drugs are not FDA-approved finished products and describes 503A compounding around patient-specific prescriptions. See Compounding and the FDA and Section 503A.
We Do Not Currently Route HCG (Human Chorionic Gonadotropin) Quote Requests
HCG has been regulated as a biologic since the FDA's March 2020 transition, and FDA rules do not allow 503A/503B compounding pharmacies to make biologics — regardless of prescription or medical necessity. Any pharmacy still offering compounded HCG is operating outside current FDA rules. HCG is available as an FDA-approved commercial product (Pregnyl / generic chorionic gonadotropin) through regular pharmacies. If FDA guidance changes, we will revisit.