COMPOUNDED SEMAGLUTIDE
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Compounded semaglutide is a custom-prepared version of the GLP-1 receptor agonist semaglutide, made by licensed compounding pharmacies. It contains the same active ingredient found in brand-name medications like Ozempic and Wegovy, but is prepared in specialized dosage forms or strengths to meet specific clinical needs.
Unlike mass-manufactured drugs, compounded semaglutide is prepared on a per-patient basis by 503A or 503B compounding pharmacies under federal and state regulations. It is prescribed when a patient has a documented clinical need that cannot be met by the commercially available product.
Common reasons patients are prescribed compounded semaglutide:
When prescribed for a legitimate clinical need, compounded semaglutide typically costs between $149 and $399 per month. Below is a general overview of semaglutide pricing.
| Medication | Type | Monthly Cost | Rx Required |
|---|---|---|---|
| Compounded Semaglutide | Compounded | $149 – $399 | Yes |
| Ozempic (brand) | FDA-Approved | ~$998 | Yes |
| Wegovy (brand) | FDA-Approved | ~$1,349 | Yes |
| Rybelsus (oral, brand) | FDA-Approved | ~$998 | Yes |
Prices vary by pharmacy, dosage strength, and consultation fees. Compounding Finder helps you compare options from licensed pharmacies so you can make an informed decision.
Compare Options — It's FreeCompounded semaglutide contains the same active ingredient as FDA-approved Ozempic and Wegovy. However, compounded versions are not individually reviewed by the FDA for safety, effectiveness, or quality. Safety depends heavily on the pharmacy preparing the medication.
Compounding Finder only works with licensed, verified compounding pharmacies to help ensure quality and safety for every patient.
Yes. Compounded semaglutide remains legal in the United States in 2026, though the regulatory landscape has changed since the FDA resolved the semaglutide shortage in February 2025.
Licensed 503A and 503B compounding pharmacies can still prepare semaglutide with a valid patient-specific prescription from a licensed provider. Compounding Finder connects you only with pharmacies that meet these requirements.
Compounding pharmacies can prepare semaglutide in several dosage forms beyond the standard injectable pen. Your prescriber can help determine which form is best for your needs.
The most common form. Injected weekly under the skin, typically in the abdomen or thigh. Available in multiple dose strengths for gradual titration.
Dissolved under the tongue for absorption. A needle-free alternative growing in popularity for patients who prefer not to inject.
Flavored lozenges that dissolve in the mouth. Another needle-free option that some patients find more convenient.
Compounded oral capsules taken by mouth. Availability varies by pharmacy and may require specific formulation techniques.
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Both contain the active ingredient semaglutide. Ozempic is manufactured by Novo Nordisk and is FDA-approved, while compounded semaglutide is custom-prepared by licensed compounding pharmacies. Compounded versions may come in different dosage forms.
Compounded semaglutide typically costs between $149 and $399 per month, depending on the dose and pharmacy.
No. Compounded medications are not individually FDA-approved. However, they are prepared by pharmacies regulated under federal (FDA) and state pharmacy board oversight. The active ingredient, semaglutide, is the same FDA-approved compound.
Yes. Licensed compounding pharmacies can still prepare semaglutide for patients with legitimate clinical needs, such as allergies to branded excipients or requirements for non-standard dosing, with a valid prescription from a licensed provider.
Yes. Compounded semaglutide is a prescription medication. You need a valid prescription from a licensed healthcare provider. Be cautious of any source offering semaglutide without requiring a prescription.
Compounded semaglutide is available as subcutaneous injections, sublingual tablets, troches (lozenges), and oral capsules. Injections are the most common and well-studied form.
Look for pharmacies that are licensed, accredited (such as PCAB accreditation), conduct third-party testing, and require a valid prescription. Compounding Finder can help connect patients with verified, licensed U.S. compounding pharmacies.
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