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Thymosin Alpha-1 is an endogenous thymic peptide that stimulates T-cell differentiation and maturation, enhances dendritic cell function, upregulates MHC class II expression, and modulates cytokine production — restoring balanced, effective immune surveillance.
FDA-approved Thymosin Alpha-1 (Zadaxin) is not commercially available in the US. Compounding pharmacies are the only domestic source for Thymosin Alpha-1 injectable preparations.
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Thymosin Alpha-1 (Tα1) is a 28-amino acid peptide originally isolated from thymus tissue that plays a central role in T-cell maturation and immune competence. It has been studied extensively for HIV, hepatitis B and C, cancer (as adjunct to chemotherapy), and chronic immune dysregulation.
In integrative and functional medicine, Tα1 is prescribed for Long COVID, MCAS, chronic Lyme, post-viral immune dysfunction, and as an immune modulator for autoimmune conditions where conventional therapies have failed.
Long COVID immune dysfunction, chronic viral infections (EBV, HHV-6), MCAS, autoimmune conditions, cancer adjunct therapy, immunocompromised states
Standard protocol: 1.6mg SubQ 2x per week for 6–12 months
Acute/intensive: 1.6mg daily for 30 days then taper
Excellent safety profile. Mild injection site reactions, transient fatigue, occasional mild fever as immune system activates. One of the safest injectable peptides available.
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