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Testosterone binds to androgen receptors, regulating muscle mass, bone density, libido, mood, energy, and red blood cell production. Compounded formulations deliver precise, patient-specific doses.
Commercial products come in fixed doses only. Compounding allows custom concentrations, unique delivery methods (creams, pellets, troches), and combinations with other hormones like DHEA — at a fraction of the cost.
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Testosterone is the primary male sex hormone. It plays a critical role in muscle development, bone density, libido, mood, energy, and cardiovascular health.
TRT is prescribed for hypogonadism in men and increasingly for hormone optimization in women — particularly post-menopausal women experiencing low libido, fatigue, and cognitive decline.
Because commercial testosterone products come in fixed doses, compounding pharmacies are the go-to source for personalized TRT protocols.
Androgen Receptor Activation
Testosterone binds to intracellular androgen receptors, modulating gene expression — regulating protein synthesis, muscle growth, and metabolic function.
Aromatization
A portion converts to estradiol via aromatase. This is essential for bone health and libido — but excess conversion causes estrogen-related side effects.
DHT Conversion
5-alpha reductase converts testosterone to DHT in certain tissues, responsible for prostate growth and hair follicle effects.
Men: Hypogonadism, low testosterone, sexual dysfunction, fatigue, muscle loss, bone density loss, mood disorders
Women: Low libido, post-menopausal hormone therapy, HSDD
Transgender: Gender-affirming masculinizing hormone therapy
Men — Injectable Cypionate: 50–200mg IM/SubQ every 7–14 days
Men — Transdermal Cream: 50–100mg/day applied to scrotum or inner arm
Women — Cream/Gel: 0.5–5mg/day topically
Dosing must be individualized based on labs (total T, free T, SHBG, estradiol).
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