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GHRP-2 is a synthetic hexapeptide that binds to the ghrelin receptor (GHSR-1a) on pituitary somatotrophs, triggering potent GH release. Unlike Ipamorelin, it also stimulates cortisol and prolactin modestly, with greater peak GH pulses.
GHRP-2 has no FDA-approved commercial equivalent. Compounding pharmacies are the only legal source for GHRP-2 injectable preparations.
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GHRP-2 (Growth Hormone Releasing Peptide-2) is a synthetic hexapeptide ghrelin receptor agonist that produces one of the most potent GH pulses among available secretagogues. It is frequently used as the GHRP component in combination protocols with CJC-1295 (GHRH analog) for synergistic GH stimulation.
Compared to Ipamorelin (a cleaner, more selective GHRP), GHRP-2 produces larger peak GH pulses but also mildly stimulates cortisol and prolactin — making it more appropriate for body composition-focused protocols where maximum GH output is desired over long-term hormone optimization.
GH stimulation for muscle building and fat loss, combined with CJC-1295 for amplified GH release, athletic performance, anti-aging, injury recovery
Standard: 100–300mcg SubQ 2–3x daily (pre-workout and at bedtime)
Combined with CJC-1295 at equal dosing for synergistic effect
Water retention, increased appetite (ghrelin effect), mild cortisol and prolactin elevation, injection site reactions. More hunger stimulation than Ipamorelin.
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