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Epithalon (Epitalon) is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) that activates telomerase — the enzyme that maintains and lengthens telomeres, the protective caps on chromosomes associated with cellular aging and lifespan. It also normalizes pineal function, improving melatonin production and circadian rhythm.
Epithalon has no FDA-approved commercial equivalent. Compounding pharmacies prepare sterile injectable Epithalon as the only legal source for human therapeutic use.
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Epithalon (also spelled Epitalon) is a tetrapeptide developed by Professor Vladimir Khavinson at the St. Petersburg Institute of Bioregulation. It is the synthetic analog of Epithalamin — a natural peptide extracted from the pineal gland.
Epithalon has been studied in over 100 clinical trials in Russia over 40+ years, showing remarkable effects on longevity, immune function, cancer prevention, and neurological health. Its primary mechanism — telomerase activation — positions it as one of the most evidence-backed anti-aging interventions available.
Anti-aging and longevity protocols, telomere maintenance, sleep improvement (circadian normalization), immune optimization, cancer prevention (adjunct research)
Typical course: 5–10mg SubQ or IM daily for 10–20 days, 2–4 courses per year
Maintenance: 5mg SubQ nightly for 10 days, 1–2x per year
Exceptionally well tolerated. Mild injection site reactions, improved sleep often reported as a side effect. No significant toxicity identified in human studies.
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