Search 7,500+ licensed pharmacies to find the best value, closest location, and fastest turnaround for
.
DHEA (dehydroepiandrosterone) is a precursor hormone produced primarily by the adrenal glands. It converts downstream to testosterone and estrogens, supporting hormone balance, energy, immune function, and sexual health.
OTC DHEA supplements vary widely in quality and purity. Prescription compounded DHEA provides pharmaceutical-grade potency, custom doses below or above OTC options, and specialized formulations like intravaginal suppositories (Intrarosa-equivalent) at a fraction of the brand price.
Compare up to 7,500 pharmacies across the USA.
DHEA (dehydroepiandrosterone) is the most abundant circulating steroid hormone in the human body and is produced primarily by the adrenal cortex. DHEA levels peak in early adulthood and decline steadily with age — falling by 80–90% between ages 25 and 70.
As a precursor to both testosterone and estrogens, DHEA plays a key role in hormone balance, energy, immune regulation, bone density, and sexual function.
Prescription compounded DHEA offers pharmaceutical-grade quality and customized dosing not available in OTC supplements, including intravaginal formulations for genitourinary syndrome of menopause (GSM).
Androgenic Precursor
DHEA and its sulfate form (DHEA-S) convert to testosterone and androstenedione peripherally in tissue, providing localized hormone effects.
Estrogenic Conversion
DHEA can also convert to estrogens via aromatization, contributing to estrogen levels in post-menopausal women.
Direct Receptor Activity
DHEA has direct activity at androgen receptors, GABA receptors, and sigma-1 receptors — contributing to mood, cognition, and neuroprotective effects.
Adrenal: Adrenal insufficiency, adrenal fatigue support
Sexual Health: Low libido (men and women), vaginal atrophy, GSM
BHRT: Foundational hormone optimization protocols
Lupus: FDA-approved at 200mg/day for SLE (prasterone)
Aging: Age-related decline in energy, bone density, and immune function
Oral/Capsule: 5–100mg/day depending on indication and sex
Transdermal Cream: 5–25mg/day topically
Intravaginal: 3.25–10mg per suppository, inserted nightly or as directed
Dose based on DHEA-S lab levels and clinical response. Women typically use lower doses (5–25mg) than men.
Common:
In women at higher doses:
Submit a quote request to find the lowest price. Quotes delivered to your inbox.
Find Lowest Price.png){kind=spacer}
