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BPC-157 is a synthetic peptide derived from a protein found in gastric juice. It accelerates healing of tendons, ligaments, muscles, and gut tissue by stimulating angiogenesis, activating growth factor signaling, and modulating nitric oxide production.
BPC-157 has no FDA-approved commercial equivalent. Licensed compounding pharmacies are the only legal source for BPC-157 preparations for human therapeutic use.
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BPC-157 (Body Protection Compound-157) is a pentadecapeptide — a chain of 15 amino acids — derived from a protein found in human gastric juice. Originally studied for GI healing, it has demonstrated broad tissue repair effects and become one of the most widely used peptides in sports medicine and functional medicine.
BPC-157 is prescribed for tendon and ligament injuries, post-surgical recovery, inflammatory bowel conditions, and neurological support. All human use requires a valid prescription from a licensed compounding pharmacy.
Angiogenesis Promotion
BPC-157 upregulates VEGF and stimulates new blood vessel formation in injured tissue — critical for healing tendons and ligaments with poor baseline blood supply.
Growth Factor Modulation
Activates the FAK-paxillin pathway and modulates EGF and FGF expression, accelerating cellular proliferation and tissue remodeling.
Gut Mucosal Protection
Accelerates mucosal healing, reduces GI inflammation, and protects against NSAID-induced gut damage.
Musculoskeletal: Tendon injuries, ligament tears, muscle strains, post-surgical recovery
Gastrointestinal: IBD, leaky gut, ulcers, NSAID-induced gut damage
Neurological: TBI recovery, nerve repair, neuroprotection
Injectable: 200–500mcg once or twice daily near the injury site
Oral capsules (GI indications): 250–500mcg twice daily
Typical course: 4–12 weeks depending on injury severity
Common (generally very well tolerated):
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