Retinoids are vitamin A derivatives that regulate cell growth and differentiation in skin tissue. Compounded retinoids allow customized concentrations, combinations with other actives (niacinamide, hydroquinone, kojic acid), and formulations in bases suited to sensitive skin.
Retinoids bind to nuclear retinoic acid receptors (RARs and RXRs), regulating genes that control keratinocyte proliferation, collagen synthesis, and melanin production. They accelerate epidermal turnover, reduce sebum, and stimulate collagen remodeling.
Commercial tretinoin is available only at 0.025%, 0.05%, and 0.1%. Compounding allows intermediate doses (e.g., 0.01%, 0.03%), combination formulas with hydroquinone or niacinamide, alcohol-free and fragrance-free bases for rosacea-prone skin, and combination anti-aging cocktails.
Tretinoin requires a prescription. Commercial tretinoin (Retin-A, Altreno) is FDA-approved. Compounded versions allow for custom concentrations and combination formulas not commercially available. Retinoids are contraindicated in pregnancy and require SPF use during treatment.
These compounded medications belong to this drug class. Click any medication to learn more and compare pharmacy prices.
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