Estrogens are the primary female sex hormones regulating the menstrual cycle, bone health, cardiovascular function, and mood. Compounded bioidentical estrogens (Biest, estriol, estradiol) are widely prescribed in menopause management, BHRT, and hormonal imbalance protocols.
Estrogens bind to estrogen receptors (ERα and ERβ) throughout the body, regulating gene expression that affects uterine lining, bone density, cholesterol metabolism, skin hydration, and neurotransmitter activity including serotonin and dopamine.
Commercial estrogen products are limited in dose, ratio, and delivery form. Compounding allows customized Biest (estradiol + estriol) combinations, transdermal creams, vaginal suppositories, and pellets precisely tailored to an individual's hormone panel results.
Compounded bioidentical estrogens are not FDA-approved as finished drug products but are legally prescribed under 503A for individual patients. The FDA has noted ongoing safety review of bioidentical compounded hormones. Patients should discuss benefits and risks with a licensed hormone specialist.
These compounded medications belong to this drug class. Click any medication to learn more and compare pharmacy prices.
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