Drug Classes

Coenzyme / Cellular Energy Drug Class

Coenzymes are essential molecules that support cellular energy production, antioxidant defense, and metabolic function. Compounded coenzyme therapies including NAD+ infusions and high-dose CoQ10 are used in anti-aging medicine, mitochondrial disorders, and chronic fatigue.

How It Works

NAD+ (nicotinamide adenine dinucleotide) is a critical coenzyme in cellular respiration and energy production, serving as an electron carrier in the mitochondrial electron transport chain. It also activates sirtuins (longevity proteins) and supports DNA repair. CoQ10 serves as a mobile electron carrier between respiratory chain complexes.

Why Compounded?

IV NAD+ infusions, high-concentration NAD+ nasal sprays, pharmaceutical-grade high-dose CoQ10, and combination mitochondrial cocktails all require compounding. Commercial supplements do not provide therapeutic-dose parenteral delivery.

Common Uses

  • Chronic fatigue syndrome / ME-CFS
  • Mitochondrial disease
  • Neurodegenerative disease support
  • Addiction recovery (NAD+ IV therapy)
  • Anti-aging and longevity protocols
  • Post-COVID fatigue
  • Statin-induced myopathy (CoQ10)

Common Compounded Medications

  • NAD+ IV Infusion Solution
  • NAD+ Nasal Spray
  • NAD+ Sublingual / Injection
  • CoQ10 Injectable
  • Nicotinamide Riboside (NR) Custom Capsules

Regulatory & Safety Notes

NAD+ for IV infusion is compounded under 503A as a patient-specific preparation. The FDA has classified certain NAD+ precursors as drug compounds when compounded for injection. IV NAD+ therapy should be administered under medical supervision. Quality and sterility standards for injectable preparations are critical.

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